Age and gender related differences in olfactory bulb glomeruli in human

ABSTRACT

The present study was designed to investigate the age and gender related differences in glome-ruli of the human olfactory bulb in normal Pakistani population. The study was conducted in the Department of Anatomy, University of Health Sciences, Lahore. The duration of the study was two years. Sixty olfactory bulbs, thirty each from male and female human cadavers [age 20-76 years] were collected from the mortuary of the King Edward Medical University, Lahore. Glomeruli were counted and their diameter was calculated from 10 micro m thick H and E stained histological sections. Statistical analysis was done using ANOVA for age related differences and Independent [t] test for gender related differences. The results showed significant decrease in the number ofglomeruli [p < 0.001] and their diameter [p < 0.05] with age. No gender related differences were observed. The number of glomeruli and their diameter both decreased with advancing age