Serological immune status of hepatitis-B in vaccinated healthy individuals
Biomedica. 2008; 24 (Jan.-Jun.): 75-77
in English
| IMEMR
| ID: emr-86002
ABSTRACT
This study was planned to assess the Hepatitis-B serological immune response in previously vaccinated students and staff members of various faculties of Lahore Medical and, Dental College Lahore. The objective was to evaluate the effectiveness of hepatitis B vaccination in prevention of hepatitis infection, chronic liver disease and recommendation of booster dose after primary course of vaccination. The study group comprised of 276 volunteers including MBBS/BDS students and 16 staff members of different faculties. Age range among students was 17-25 years whereas staff members were 30-50 years in age. Among 276 volunteers 46% were males and 54% were females. The levels of hepatitis B surface antibodies were assessed in blood/ serum by enzyme linked immunosorbant assay [ELISA] technique. Among 276 volunteers 230 SIGMA had detectable antibodies against hepatitis B surface antigen [aHBs] while 46 [18%] showed no detectable level of antibodies against hepatitis B surface antigen [aHBs] in their serum. The titer of antibodies against hepatitis B surface antigen [aHBs] was low among staff members who were in age group of 30-50 years [n4, 0.25%] A decline in titer was observed during adolescence
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Students, Dental
/
Students, Medical
/
Enzyme-Linked Immunosorbent Assay
/
Age Factors
/
Immunization, Secondary
/
Immunization
/
Hepatitis B Antibodies
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Biomedica
Year:
2008
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