Evaluation of diuretic activity of musli safed [chlorophytum arundinaceum baker] in albino rats

ABSTRACT

Musli Safed [Chlorophytum arundinaceum Baker] powder in triturated form has been evaluated for its diuretic activity at dose levels of 1 g and 3 g/kg in albino rats. The diuretic effect of the drug has been compared with standard diuretic agent frusemide [Lasix]. It was found that Musli Safed possesses the efficacy to bring about significant increase in urine output at the dose level of 3 g/kg. Continuous treatment of the animals with Musli Safed for a week resulted in significant increase in the urinary concentrations of Na[+], K[+] and Cl[-] at the close of 3 g/kg. These findings indicate that Musli Safed is a good diuretic agent