[Leukocyte adhesion deficiency syndrome and report of three cases]
Iranian Journal of Otorhinolaryngology. 2008; 20 (3): 161-164
in Persian
| IMEMR
| ID: emr-87184
ABSTRACT
Leukocyte adhesion deficiency syndrome [LADS] is a rare inherited immunodeficiency in which the frunction of leukocytes, particularly the phagocytes are disturbed. In the present study, we report three cases with LADS [2 male infants and 1 female child] who had a history of delay in separation of umbilical cord. One infant admitted for skin infection and two patients admitted in hospital following bacterial and fungal infections in nose and finger. All cases had a remarkable leukocytosis, neutrophilia and decreased of CD 11 and CD 18. LADS is a congenital syndrome causes recurrent bacterial and fungal infections. Usually all patients have a history of delayed separation of umbilical cord
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Phagocytes
/
Bacterial Infections
/
Umbilical Cord
/
Child
/
CD18 Antigens
/
CD11 Antigens
/
Infant
/
Leukocytosis
/
Mycoses
/
Neutrophils
Type of study:
Case report
Limits:
Female
/
Humans
/
Male
Language:
Persian
Journal:
Iran. J. Otorhinolaryngol.
Year:
2008
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