Treatment and vaccination for hepatitis C: present and future
JAMC-Journal of Ayub Medical College-Abbotabad-Pakistan. 2008; 20 (1): 129-133
in English
| IMEMR
| ID: emr-87392
ABSTRACT
Hepatitis C is caused by Hepatitis C Virus [HCV], detriments the quality of life of 170 million people around the globe. Although, much has been known about the biology of the virus in recent years, a complete cure of hepatitis C remains difficult in a large majority of patients. The current treatment regimen comprising pegylated interferon alpha and ribavirin has sub-optimal effectiveness especially in patients infected with HCV genotype 1. The development of an effective vaccine against the virus as well as a potent anti-viral therapy remains urgently needed. Herein, we give a brief overview of the molecular biology of hepatitis C and the postulated mechanisms of hepatitis C pathogenesis. The issues surrounding the current treatment of hepatic C, the promising new therapies on the horizon and the experimental strategies to develop a vaccine have also been discussed in a greater detail
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Viral Hepatitis Vaccines
/
Viral Vaccines
/
Vaccination
/
Hepatitis C
/
Hepacivirus
/
Molecular Biology
Limits:
Humans
Language:
English
Journal:
J. Ayub Med. Coll.-Abbotabad-Pak.
Year:
2008
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