Cyclopia with polydactyly and congenital heart disease in one of discordant twins: acase report

ABSTRACT

Cyclopia is a rare congenital abnormality consisting of fused orbits and a single eye and is the most extreme form of alobar holoprosencephaly. It is an uncommon congenital anomaly resulting from arrest of the development of the anterior end of the neural plate. It is always associated with abnormalities of the brain. In one study, cyclopia was reported in one discordant twin only[1]. In this report, we describe a case of cyclopia that was associated with ploydactyly and congenital heart disease in a female infant who was one of discordant twins