Biochemical parameters in chronic fascioliasis

ABSTRACT

Serum lipids, liver enzymes and total bile acids were measured in chronic Fasciola [cholestatic and non-cholestatic] patients. Variations in the biochemical parameters between infected and control groups were detected and typified by considerably higher serum triglycerides [TG, P < 0.001], alkaline phosphatase [ALP, P < 0.001] and total bile acids [TBA, P < 0.001] in the infected group. For cholestatic patients, TG, very low density lipoprotein [VLDL], aspartate aminotransferase [AST], alanine aminotransferase [ALT], gammaglutamyl transferase [GGT] and ALP were statistically higher [P < 0.001 for each comparison] and total cholesterol [TC]; low density lipoprotein[LDL] and high density lipoprotein [HDL], were statistically lower than non-cholestatic patients [P = 0.02, < 0.001, < 0.001 respectively]. No statistically significant differences were found for the TC, HDL, VLDL, ALT, AST and GGT between non-cholestatic patients and healthy controls