Molar pregnancy - experience at a tertiary care hospital of South Punjab

ABSTRACT

To determine the frequency, clinical presentation and management outcomes of molar pregnancy. Descriptive cases series. Department of Obstetrics and Gynaecology Unit-II. Bahawal Victoria Hospital, Bahawalpur, from January 2005 to December 2007. The case records of all the gestational trophoblastic cases during the study period were analyzed regarding their history, clinical examination, investigations, treatment and follow up. The main outcomes were measured in terms of duration, antecedent pregnancy, investigations, treatment and follow up. There were a total of 21499 admissions during study period which included 54 cases of molar pregnancy. Hence frequency of Molar pregnancy was 2.5/1000 pregnancies. Most of the patients belonged to the extremes of ages. Most common presenting complaint was bleeding per vagina in 39[72.2%]. Out of 54 patients, suction evacuation was done in 51[94.4%] patients and in only 3[5.5%] patients, ended up in hysterectomy. Forty one [75.9%] patients received no adjuvant therapy, 13[24.1%] received chemotherapy. Among all 54 cases, 51[94.4%] patients fully recovered and 3[5.6%] died because of extensive disease and reported late. In this series, frequency of molar pregnancy was as equal as in different parts of the world. Proper management in the early stages influences the outcome of the disease. Hence the key point of whole discussion is to detect the disease in early stage to decrease the mortality and morbidity of patients