Does adding garlic [Allium sativum] with antidiabetic therapy help achieving better glycemic control in type 2 diabetic patients
Medicine Today. 2008; 6 (1): 131-136
in English
| IMEMR
| ID: emr-89069
ABSTRACT
With high incidence of diabetes and a wide spread belief among the general public that garlic has beneficial effects on cardiovascular risk factors., we designed a study to evaluate the blood glucose lowering effects and potential adverse effects of garlic in patients with type 2 diabetes mellitus. The study was a 12 weeks randomized, single-blind placebo controlled study, comparing the additional blood glucose lowering effects of dried garlic powder tablet 300 mg [standardized to provide 1.3% allicin equivalent to 0.6% allicin] twice daily combined with standard anti diabetic therapy [which the patient is already taking] with that of standard antidiabetic therapy alone in type 2 diabetic patients. At the end of 12 weeks it was found that changes in blood glucose [P <0.01] and cholesterol [P <0.001] were significantly different between the garlic and placebo groups. Adding garlic to an anti diabetic regimen could be a good and safe method to achieve a good glycemic control in type 2 diabetic patients. Long term clinical trials at different doses of garlic is needed to further strengthen the current findings:
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Blood Glucose
/
Allium
/
Cholesterol
/
Risk Factors
/
Treatment Outcome
/
Glyburide
/
Diabetes Complications
/
Diabetes Mellitus, Type 2
/
Hyperglycemia
/
Hypoglycemic Agents
Type of study:
Controlled clinical trial
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Med. Today
Year:
2008
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