Invasive mole as acute abdomen

ABSTRACT

The disease spectrum in gestational trophoblastic disease [GTD] varies from benign to malignant. In most cases it can be treated successfully but sometimes even a hydatidiform mole can be fatal if it remains unattended. It is an important condition that can be diagnosed and cured with chemotherapy. The gestational trophoblastic disease [GTD is a proliferative anddegenerative disorder of placental elements and includes complete and partial mole [90%] invasive mole [5-8%] choriocarcinoma [1-2%] and placental site tumour [1-2%].[1] World Health Organization classification divides GTD into the premalignant disorders which include partial and complete hydatidiform moles and the malignant disorders of invasive mole which, include choriocarcinoma and placental site tumours. Incidence is higher in Africa and Asia with geographical and racial variations.[2] The reported incidence of molar pregnancies in Europe and North America is 0.2-1.5per 1000 live births