[QT-Dispersion as a potential marker in prognosis of acute myocardial infarction]

ABSTRACT

QT dispersion in a 12 lead ECG represents the heterogeneity of ventricular repolarization. The prolongation of QT-interval dispersion increases the risk of coronary heart disease, ventricular arrhythmia, and sudden cardiac death in patients with myocardial infarction. We aimed to investigate the prognostic value of QT-dispersion in patients with acute myocardial infarction. A total number of 79 patients with acute myocardial infarction and 21 healthy controls were recruited. The QT-dispersion was estimated using a 12-lead surface electrocardiogram, 24 hours and 4-6 days after myocardial infarction. In patient group, the average QT-dispersion was 92.8 +/- 42.2 ms and 80.3 +/- 33.4 ms after 24 hours and four days respectively; whereas in control group it was 47.1 +/- 16.8 ms [p<0.001]. The relative frequency of arrhythmia in patients was 24%. Our study showed that the overage of QT-dispersion of arrhythmiain patients was significantly different and higher [p<0.05] compared to patients without arrhythmia. We showed that increased QT-dispersion is a potential marker in prognosis of patients with acute myocardial infarction