effect of exercise on plasma acylated ghrelin concentrations and gastrocnemius muscle mRNA expression in male rats

ABSTRACT

Ghrelin is a gut hormone predominantly produced by the stomach and, to a lesser extent, by other regions of the gastrointestinal tract. Ghrelin circulates in the bloodstream in two different forms acylated [or n-octanoylated] and unacylated [or des-octanoylated or des-acylated]. The purpose of this study was to examine the effect of 12 weeks training on plasma acylated ghrelin concentrations and gastrocnemius muscle mRNA expression in male rats. Twenty adult Wistar male rats [8 weeks old, 280 +/- 20 g] were used. Animals were randomly divided into experimental [EX, n = 10, V=34m/min]