Long-term effects of processed Berberis vulgaris on some metabolic syndrome components
IJEM-Iranian Journal of Endocrinology and Metabolism. 2009; 11 (1): 41-47
in Persian
| IMEMR
| ID: emr-91203
ABSTRACT
Metabolic syndrome is complex of metabolic disorders that correlates with cardiovascular disease. This study aimed at investigating the effect of processed Berberis vulgaris [B.vulgaris] on some metabolic syndrome components. Participants, type2 diabetics, were recruited in a randomized controlled clinical trial [n = 57] and randomly assigned into three groups 1] processed B.vulgaris [n =19], 2] apple vinegar group [n =19] and 3] control group [n =19]. Height, weight, serum total cholesterol, HDL-, LDL-cholesterol, triglycerides, glucose and insulin concentrations were measured at baseline and at the end of the 8th week and BMI, total/HDL-cholesterol ratio and insulin resistance were estimated. Processed B.vulgaris group showed no significant effects on BMI, total cholesterol, triglycerides and glucose concentrations, whereas LDL-cholesterol concentration [22.48 +/- 35.44mg/dl] and total/HDL-cholesterol ratio [2.56 +/- 4.87] significantly decreased and HDL-cholesterol concentration [12.33 +/- 20.58mg/dl] increased [P < 0.05]. No significant effect on lipid profiles was found in the apple vinegar group. Increased insulin concentration and insulin resistance was observed in all of these groups [P < 0.001], independent of processed B.vulgaris and apple vinegar effects. Findings of the present study showed the beneficial effects of processed B.vulgaris on certain atherosclerosis risk factors
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Triglycerides
/
Berberine
/
Blood Glucose
/
Randomized Controlled Trials as Topic
/
Risk Factors
/
Berberis
/
Metabolic Syndrome
/
Atherosclerosis
/
Insulin
/
Cholesterol, HDL
Type of study:
Controlled clinical trial
Limits:
Humans
Language:
Persian
Journal:
Iran. J. Endocrinol. Metab.
Year:
2009
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