impact of toxic heavy metals on the hematological parameters in common carp [Cyprinus carpio L.]

ABSTRACT

The aim of the present investigation was to determine the effect of heavy metal pollutants such as cadmium, chromium, nickel and lead in aquatic system on common carp [Cyprinus carpio L.] by using a set of biochemical parameters. The experimental group of fish was exposed to a sublethal concentration of 5 mg/L of combined [Cd+Pb+Cr+Ni] metal solution containing 1.25 mg/L of each metal ion [1/10th of LC 50/48 h] for a period of 32 days. The results indicated that the values of the hemoglobin were in the range of 55.30 +/- 1.20 g/L to 74.55 +/- 1.33 g/L [p < 0.001] and the packed cell volume was in the range of 26.72 +/- 0.26% to 30.68 +/- 0.43% [p < 0.01]. Concentrations of red blood cells, blood glucose and total cholesterol were significantly elevated. The level of serum iron and copper was increased. The results showed the decreased activity of vitamin C during chronic exposure to toxic heavy metals, which indicates the presence of reactive oxygen species-induced peroxidation. The study suggested that the presence of toxic heavy metals in aquatic environment has strong influence on the hematological parameters in the fresh water fish common carp [Cyprinus carpio L.]