Alpha-methyldopa hepatotoxicity in pregnancy
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2009; 19 (2): 125-126
in English
| IMEMR
| ID: emr-91612
ABSTRACT
12-week pregnant, 33-year-old African American female, presented with jaundice and change in urine colour. Liver function tests revealed raised transamines and normal alkaline phosphatase. She was started on methyldopa 6 weeks prior to presentation. After initial negative investigations including viral and autoimmune hepatitis, she was given prednisone for methyldopa induced hepatitis. Two weeks later, repeat enzymes revealed normal values. Important clinical and management points related to methyldopa induced hepatotoxicity are discussed
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pregnancy
/
Prednisone
/
Hepatitis, Autoimmune
/
Chemical and Drug Induced Liver Injury
/
Hepatitis, Viral, Human
/
Jaundice
/
Methyldopa
Type of study:
Case report
Limits:
Female
/
Humans
Language:
English
Journal:
J. Coll. Physicians Surg. Pak.
Year:
2009
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