Age specific histologic types of carcinoma breast in Malaysians

ABSTRACT

The influence of age on various histological types of breast cancer at both age < 50 years and > 50 years to simulate menopause was studied retrospective from 2002 to 2004 in Malaysia. One hundred and fifty five cases were reviewed. Ninety two cases recorded at age < 50 years, 60 [65.2%, 95%CI 54.6 - 74.8%] were infiltrating ductal carcinoma in 11[12.0%, 95% CI 6.1-20.4%], ductal carcinoma in situ [DCIS] in 9 [9.8%, 95% CI 4.6-17.8%], medullary carcinoma in 6 [6.5%, 85%CI 2.4-13.6%], invasive lobular carcinoma in 4 [4.3%, 95%CI 1.2-10.8%], mucinous carcinoma and poorly differentiated carcinoma in 2 cases [2.2%, 95%CI 0.3-7.6%]. At > 50 years of age, 63 cases were recorded. Forty seven [74.6%, 95%CI 62.0- 84.7%] cases were of infiltrating ductal carcinoma, ductal carcinoma in situ in 9 [14.3%, 95%CI 6.7-25.4%], mucinous carcinoma in 5 [7.9%, 95%CI 2.6-17.6%], medullary carcinoma [8.5%] and papillary carcinoma in 1 case each [1.6%, 95%CI 0.0-8.5%]. Infiltrating ductal carcinoma was the commonest histology at both age < 50 years and > 50 years