Hyperglycemia and mortality in critically ill patients
Pakistan Journal of Medical Sciences. 2009; 25 (2): 232-237
in English
| IMEMR
| ID: emr-92409
ABSTRACT
To analyze the relation between serum glucose concentration and hospital outcome across the critically ill patients. A single-centre, retrospective study was performed at surgical and medical intensive care unit. Admission glucose, mean morning glucose, mean glucose, maximal glucose and time-averaged glucose levels were calculated for each patient. The time-averaged hyperglycemia was defined as the area under the curve above the upper limit of normal, divided by the total length of stay. Of 300 patients with a median stay of 16 days, the mortality rate was 32%. Mean fasting glucose was 121 mg/dl in survivors versus 160 mg/dl in non survivors [P=0.001]. Mean admission glucose was 127 mg/dl in survivors versus 142 mg/dl in non survivors [0.03]. Median time-averaged hyperglycemia was 4 mg/dl in survivors versus 17.5 mg/dl in nonsurvivors [P < 0.006]. The area under the receiver operator characteristic [ROC] curve was 0.59 for time-averaged glucose and 0.73 for mean fasting glucose. Whereas time-averaged hyperglycema is a useful assessment for glucose control in critically ill patients, it has no priority to admission glucose and mean fasting glucose for outcome prediction
Search on Google
Index:
IMEMR (Eastern Mediterranean)
Main subject:
Blood Glucose
/
Survival Rate
/
Retrospective Studies
/
Mortality
/
Treatment Outcome
/
Critical Illness
/
Intensive Care Units
/
Length of Stay
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Pak. J. Med. Sci.
Year:
2009
Similar
MEDLINE
...
LILACS
LIS