Coronary heart disease; lipid abnormalities as predictor in offspring of premature coronary heart disease patients

ABSTRACT

This study was conducted to perform serum lipid profile in off springs of premature coronary heart disease [CHD] patients and age and sex matched normal controls and compare the results of two groups. A cross sectional study. 250 off springs of diagnosed premature CHD patients were selected from Punjab institute of cardiology, Lahore and Services hospital, Lahore. 50 age and sex matched normal controls were selected from different areas of Lahore. Serum total cholesterol [TC], serum triglycerides [TG] serum low density lipoprotein-cholesterol [LDC-c] and serum high density lipoprotein cholesterol [HDL-c] was performed. Serum TC, TG, LDL-c of off springs of premature CHD patients was increased as compared with normal controls. Serum HDL-c of all the subjects of off springs of premature CHD patients was decreased as compared with normal controls. Off springs of premature CHD patients are more prone to develop lipid abnormalities as compared with normal controls