unusual variant of multiple endocrine neoplasia syndrome type IIA

ABSTRACT

Multiple Endocrine Neoplasia syndrome type IIA typically includes medullary thyroid cancer, pheochromocytoma and/or primary hyperparathyroidism. Other thyroid cancers are uncommonly found with this syndrome. We present a fifty-eight years old female patient with hypercalcemia secondary to primary hyperparathyroidism and an associated non-functioning papillary thyroid carcinoma. The diagnosis was made pre-operatively and the patient underwent resection of parathyroid adenoma and total thyroidectomy. No other endocrine abnormality was detected during follow-up period of five years. We reviewed the association of the two and other endocrine abnormalities