Hepatoprotective activity of Phyllanthus reticulatus

Two partially purified organic fractions designated by PR1 and PR2 of the fat free ethanol [95%] extract of aerial parts of Phyllanthus reticulatus were tested for the hepatoprotective activity in rats against CCl[4]-induced liver damage. The rats receiving the fractions showed promising hepatoprotective activity as evident from significant changes of pentobarbital-induced sleeping time, changes in serum levels of sGPT, sGOT, sALP and bilirubin and also from histopathological changes as compared to CCl[4]-intoxicated rats