Polycystic ovarian disease a study of 14 cases

ABSTRACT

Fourteen cases of polycystic ovarian disease were diagnosed. The diagnosis was based on clinical presentation, laboratory data, and histological picture for the nine patients who had an ovarian wedge resection. The results of the treatment of these cases were discussed comparing the return of menstruation, ovulation and pregnancy rate between the group treated with clomiphene citrate and the group who failed to respond to clomiphene and were managed by ovarian wedge resection. The conclusive results of our series at both the diagnostic and therapeutic level were in agreement with findings of various authors. At the diagnostic level we found that although the diagnosis of polycystic ovarian disease is a clinical one, the elevated serum LH and testosterone [plasma] will support the diagnosis. The therapeutic value of clomiphene citrate is rather limited but we still believe that those cases diagnosed clinically as polycystic ovarian disease should not be subjected to invasive procedure before they were given at least six months course of clomiphene supplemented by LH. The medical literature and opinions of various authors are discussed regarding diagnosis, treatment and pathogenesis of polycystic ovarian disease