Some biochemical indices of diabetic vascular disease

ABSTRACT

Some biochemical indices related to diabetic complications were assessed in 86 diabetics and results compared with 20 normal controls. Cholesterol, beta-lipoprotein, and plasma fibrinogen levels were significantly higher in with vascular complications when compared with normal controls. Triglycerides were elevated in all groups, bi in patients with retinopathy and venous dilation. There was a suggestion that triglycerides were related in dietary carbohydrate in maturity onset diabetics. It appears therefore that elevation of lipids is correlated with the features of diabetic vascular disease. Elevation of lipids secondary to nephropathy establishes a vicious cycle in the course of the disease. Higher levels of lipids can also explain the increased platelet adhesiveness and aggregation