Serum procollagen III propeptide and plasma fibronectin in chronic hepatosplenic schistosomiasis

ABSTRACT

Hepalosplenic schislosomiasis is a chronic disease of the liver characterized by granulomalous reaction, portal fibrosis, and presinusoidal portal hypertension. This study was carried on twelve patients fulfilling pre-established clinical, biochemical and histologic criteria for the diagnosis of chronic hepatic schistosomiasis. The serum procollagen III propeptidc [PIIIP] level was significantly higher in those patients compared to the control individuals and insignificant increase in plasma fibrohectin level was noticed in chronic hepatic schistosomiasis