Synthesis of some new imidazolinones of expected antimicrobial activity
Bulletin of Faculty of Pharmacy-Cairo University. 1991; 29 (3): 21-5
in English
| IMEMR
| ID: emr-95325
ABSTRACT
The action of hydrazine on 5-cinnamylidene-2-ethylthio-3-phenylhydantoin [Ic] gave 1-amino-2-anilino-4-cinnamylidine- delta[2] imidazolin-5-one [II]. The latter was deaminated with nitrous acid to yield 2-amino-4-cinnamylidene- delta[2]-imidazolin-5-one [IVa] which was also obtained from Ic by the action of ammonium acetate or Ia by the action of aniline. Compound II was condensed with aromatic aldehydes to give the corresponding Schiff's bases VIa-f. A number of 2-substituted aminoimidazolinones IVb-j and VIIIa-d were also prepared. Some of the obtained compounds showed antimicrobial activity
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Imidazoles
Language:
English
Journal:
Bull. Fac. Pharm.-Cairo Univ.
Year:
1991
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