Clomiphene citrate induced pregnancies and their outcome

ABSTRACT

Since its introduction in I960, Clomiphcnc Citrate [CO] is probably one of the most widely used medication in infertility practice. In this study one hundred and sixty five patients of interility were treated with CC and 80 [48.5%] conceived. Ninety percent became pregnant within the first 3 cycles of their ovulation confirmed therapy and 60% of them required the minimum standard dose [50 mgx5 days]. Pregnancy wastage was to the extent of 31.3% with the abortion rate of 26.3% following CC therapy and these rates are similar to the figures expected from the infertile population under discussion. Surprisingly the rate of twinning in our study [1.25%] was not different from that reported in the general population [1.6%]. Expectedly the incidence of intervention was high due to preciousness of this pregnancy for obvious reasons