Protein electrophoretic pattern in healthy and pulmonary tuberculosis subjects

ABSTRACT

Serum protein electrophoresis of 30 healthy subjects [20 males and 10 females] and 30 pulmonary tuberculosis patients [16 males and 14 females], of different age groups, was carried out on cellulose acetate membrane. It was observed that in healthy subjects, the mean concentrations of total protein, albumin and beta-fraction of globulin were higher in males, while alpha-I and alpha-2 were higher in females. No significant difference was noted in the levels of total globulins and gamma globulin in both sexes. On the other hand, the pattern in pulmonary tuberculosis patients during active stage of the disease showed that the albumin content was decreased while the mean levels of total protein and all the globulin fractions were increased in both males and females. alpha-2 and Gamma globulin values were highly increased and a slight increase in the concentration of total protein and beta-globulin fraction was found