[Drug interaction between iron and oxytetracycline absorption in swine]
Journal of the Faculty of Veterinary Medicine-University of Tehran. 1996; 50 (3-4): 23-29
in Persian
| IMEMR
| ID: emr-96040
ABSTRACT
Iron is known to interfere with the absorption of simultaneously taken tetracycline derivatives. In order to avoid this interaction a suitable time interval should be regarded between the administration of tetracycline and iron in swine. The drug interaction is probably due to the formation of chelates in the gastrointestinal tract. A time interval of about 3 hours however is sufficient to avoid drug interaction between iron and tetracyclines. The present study was intended to demonstrate the interference between iron [in rusty water] and oxytetracydine absorption in swine. But the amount and/or the type of iron used, may not significantly influence the absorption of simultaneously ingested tetracycline
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Oxytetracycline
/
Iron
Limits:
Animals
Language:
Persian
Journal:
J. Fac. Vet. Med.-Univ. Teheran
Year:
1996
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