Primary pulmonary Hodgkin's disease [case report]

ABSTRACT

Lung involvement in Hodgkin's disease is usually associated with nodal involvement and is due to direct extension from mediastinal nodes. Primary pulmonary Hodgkin's disease is a rare disease. This disease occurs most frequently in the older women. The present case was a 54-year-old woman who was presented with fever, dry cough and weight loss since the last three months. There was no evidence of hepatosplenomegaly and peripheral lymphadenopathy. Radiological investigations revealed bilateral pulmonary nodular lesions but no mediastinal lymphadenopathy. Cyto-pathology assessment of the sample which was taken based on bronchoscopic and CT results did not help with diagnosis of the disease. As a last resort, open lung biopsy was done and a diagnosis of Hodgkin's disease was made. The final diagnosis was primary pulmonary Hodgkin's disease. Although primary pulmonary Hodgkin's is a rare disease, it should be considered as one of the causes of bilateral pulmonary nodular lesions