Comparison of the analgesic effects of peripheral injections of streptomycin/bupivacain and anhydrous glycerol in relieving trigeminal neuralgia

ABSTRACT

Trigeminal neuralgia is an idiopathic, paroxysmal, painful, unilateral affliction of the face, evoked by trivial stimuli to the specific trigger lone, lasting from a few seconds to two minutes. Medical and surgical treatment options are available with varying degree of efficacy. The objective of the study is to compare the analgesic effects of streptomycin/bupivacain versus anhydrous glycerol injection in trigeminal neuralgia. Sixty patients were selected via Non- probability, purposive sampling technique, at the department of oral and maxillofacial surgery, king Edward Medical University Mayo Hospital Lahore, from 1[st] June 2008 to 30[th] Nov 2008. Patients were randomly distributed in to 2 equal groups. In Group A streptomycin/bupvivacain injection was administered, in Group B 1 ml anhydrous glycerol injection was administered. Patients were reviewed after one week, one month, three month and six months postoperatively. 25 [83.34%] patients of Group A had excellent pain relief, 03 [10%] had good results and 02 [6.66%] patients had poor results. 28 [93.34%] patients of Group B had excellent results, and 2 [6.66%] patients had good results while none of the patients had poor results. The p value for these two procedures is not significant [p=0.378]. The analgesic effect of streptomycin/bupvivacain injection is same as glycerol injection in trigeminal neuralgia. They are simple, quick, and easy to perform, and can be used as outpatient procedures. Trigeminal neuralgia, anhydrous glycerol, streptomycin, Visual analogue scale