High frequency of hand foot syndrome with capecitabine
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2010; 20 (6): 421-422
in English
| IMEMR
| ID: emr-98109
ABSTRACT
A hospital based cross-sectional retrospective study was conducted to determine the frequency of hand foot syndrome [HFS] with Capecitabine as a single agent and in combination with Oxaliplatin. The study included 43 consecutive cases of colorectal carcinoma and conducted from June till December 2008. Patients on palliative care were excluded. SPSS was used for the application of chi-square test, by keeping the level of significance as p<0.05. Fifteen [34.9%] patients developed HFS, 10 in the single-agent and 5 in the combination group. No significant association of HFS with either regimens was noted [p=0.876]
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Syndrome
/
Colorectal Neoplasms
/
Cross-Sectional Studies
/
Drug Therapy, Combination
/
Hand Dermatoses
/
Antimetabolites, Antineoplastic
Type of study:
Prevalence study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
J. Coll. Physicians Surg. Pak.
Year:
2010
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