Effect of glycemic control on diabetic dyslipidemia

ABSTRACT

To determine whether good glycemic control has an effect on lipid profile in diabetics. Cross- sectional study. Department of Medicine, Combined Military Hospital Lahore; June to December 2007. After taking relevant history and physical examination, serum urea, creatinine, thyroid stimulating hormone, bilirubin, alanine transaminase and HbA1c were measured. Blood samples for determination of fasting plasma glucose, serum total cholesterol, triglycerides, HDL and LDL levels were collected in a fasting state. Patients were divided into two groups based on HbA1c levels. They were compared using SPSS 13. 42 patients had good glycemic control and 58 had poor control. The two groups were age and weight matched. 43 patients had abnormal lipid profiles. Serum total cholesterol and triglycerides were lower and HDL levels higher in the good control group but serum LDL levels were equal. Good glycemic control improves lipid profile in patients with type 2 diabetes mellitus