Evaluation of possible oral side effects of cinnamol mouthwash

ABSTRACT

Cinnamol mouth wash has deodorant antimicrobial effects. Cinnamol - the basis of this product - can incite allergic stomatitis [lip swelling, bulb, keratosis, oral ulcer and squamous cell carcinoma]. The aim of this study was to detect cinnamol mouth wash side effects. This double blind clinical trial study was done on 50 dental students of Yazd dental faculty. After oral examination, subjects were entered into a randomized double blind study. Exclusion criteria were systemic disorders, allergic symptoms, multiple drug use and recurrent oral ulcers. 25 cases were asked to rinse with cinnamol and 25 with placebo [peppermint] for 10 days. Oral manifestations were examined during and at the end of the study. Data were analysed by chi-square test. Fifty subjects [18 women and 32 men] were examined. The mean age was 26.1 [age range 21-44]. No significant problem was seen in the control group. In the case group, only one lip swelling was observed. No adverse effect was observed with the use of cinnamol mouth wash. May be less cinnamol concentration in cinnamol mouth wash in addition to short time use and short time rinse is the susceptible cause of this finding. Long term studies with greater sample size are recommended