Relationship between leukocyte count, erythrocyte sedimentation rate, blood pressure, body mass index, and type 1 diabetes mellitus

ABSTRACT

Emerging data suggest that diabetes mellitus [DM] [type 1 and type 2] may play a role in the increasing level of leukocyte [WBC] count and erythrocyte sedimentation rate [ESR]. Because of few prospective studies have addressed this issue, this study examined the relation between DM type 1 and the total, differential leukocyte count, ESR, body mass index [BMI], and systolic blood pressure [SBP] and diastolic blood pressure [DBP] for 228 participants: 78 men and 150 women have been measured. Among 78 men, there are 21 diabetic [13 below 40 years old] and among 150 female subjects, 33 develop diabetes [18 below 40 years old]. Smoking status has no real effect in the present data. All data were collected from Central Tripoli Hospital and Yefren Hospital. In male but not female DM type 1 showed significant [p<0.05] effect on the total WBC count and the percentages of differential WBC [lymphocytes% and neutrophils%] compared with the normal group. However, BMI and ESR were found to be significantly [p<0.05] effected by DM type 1 in both genders. These findings are consistent with the hypothesis that an activation of leukopoiesis may play a role in pathogenesis of DM