significance of Helicobacter pylori infection in uraemic patients

ABSTRACT

Helicobacter pylori play an important role pathogenesis of gastritis and peptic ulcer disease in uraemic patients. To assess the prevalence of helicobacter pylori infection in uraemic, and to find the relationship endoscopic findings and the H. pylori infection. Forty patient with chronic renal failure were studied and compared with 38 patients with dyspepsia without any known history of renal disease. All underwent upper gastrointestinal endoscopy and antral biopsies were taken for detection of H.pylori infection using the rapid uraease test as agoldstandard for confirmation of the infection. The prevalence of H.pylori infection was 32.5% in uraemic patient and abnormal endoscopic finding were detected in 70% of the patients with abnormal endoscpic findings. The prevalence of H.pylori in uraemic patients is lower than in patients with the normal renal function, but the difference is not significant statistically