Comparison of methods for HIV isolation from monocytes and lymphocytes of seropositive asymptomatic hemophiliacs and homosexuals
Braz. j. med. biol. res
;
24(11): 1087-92, 1991. tab
Article
in English
| LILACS
| ID: lil-105485
RESUMO
1. Since monocyte-macrophages have been recognized as HIV targets in addition to CD4+ T-lymphocytes, we have evaluated HIV infection of purified peripheral blood mononuclear cell fractions obtained from 10 seropositive asymptomatic hemophiliacs and compared with that of 10 assymptomatic homosexual patients. 2. HIV was isolated more frequently from the lymphocytes than the monocytes of both groups of patients. 3. HIV preferential replicated in phytohemagglutinin-stimulated lymphocytes compared with growth factor-treated monocytes. Monocytes did not preferentially harbour HIV in either group
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Index:
LILACS (Americas)
Main subject:
Monocytes
/
T-Lymphocytes
/
Homosexuality
/
HIV
/
HIV Seropositivity
/
Hemophilia A
Limits:
Humans
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1991
Type:
Article
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