Human leukocyte a and B antigen, gene and haplotype frequencies in the population of the city of Säo Paulo in Brazil
Braz. j. med. biol. res
;
25(1): 39-47, 1992. tab
Article
in English
| LILACS
| ID: lil-108998
RESUMO
Antigen, gene and haplotype frequencies are imnportant data for population analysis, poaternity exclusion testing, genetic studies, and for organ transplantation selection. We have studied the class I histocompatibility antigens of 617 unrelated individuals from the city of Säo Paulo, Brazil, to determine antigen and gene frequencies of HLA-A and 28 HLA-B antigens. Estimated haplotype frequencies were also determined, as well as the genetic distances of this population from European Caucasian and Negro populations. A previously unknown linkage disequilibrium was detected for A23-B49 and a clear trend towards antigen frequencies intermediate between Caucasoid and Negro populations was observed
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Index:
LILACS (Americas)
Main subject:
Antigens, CD
/
Histocompatibility Antigens
Limits:
Adult
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1992
Type:
Article
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