Preliminary report on the application of the coaggutination test for rapid diagnosis of cholera in the upper Solimöes river area in the Brazilian Amazon region
Braz. j. med. biol. res
;
25(4): 375-8, 1992.
Article
in English
| LILACS
| ID: lil-109042
ABSTRACT
The conventional diagnosis of cholera depends on complex bacteriological procedures. Coagglutination is a simnple, rapid, inexpensive and efficient technique for the presumptive diagnosis of cholera. Of 840 fecal samples from suspected cases of cholera examined at Tabatinga (State of Amazonas, Brazil) 31 (3.6%) were confirmed by culture and 29 of then were also positive by the coagglutination test performed directly on the fecal enrichment broth (alkaline peptone water). About 90% of the positive coagglutination results were obtained after-5-h incubation at 37 grade C and the sensitivity, specificity and accuracy of the method were 93.5%, 99% and 98.8%, respectively. relative to the culture results, coagglutination yielded two false-negative and eight false-positive results. The coagglutination test for cholera can provide a rapid and reliable tool for epidemiological studies and for the planning of more effective measures against cholera
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Index:
LILACS (Americas)
Main subject:
Vibrio cholerae
/
Blood Coagulation Tests
/
Cholera
Type of study:
Diagnostic study
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1992
Type:
Article
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