Pharmacokinetic profile of two different pharmaceutical forms of theophylline (a slow release tablet and a syrup) after multiple dose administration to healthy human volunteers
Mem. Inst. Oswaldo Cruz
;
88(1): 155-8, jan.-mar. 1993. tab, ilus
Article
in English
| LILACS
| ID: lil-117665
ABSTRACT
Due to the narrow therapeutic range of theophyline, plasma concentrations of this drug are monitored in patients undergoing chronic therapy. Slow-release preparations avoid the fluctuations in plasma levels and improve patient compliance. In this study, we have compared the pharmacokinetic profiles of a theophylline slow-release tablet and a syrup form, when administered in multiple doses to healthy adult volunteers. The classification based upon releasing patterns is confirmed
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Theophylline
/
Pharmacokinetics
Limits:
Humans
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
1993
Type:
Article
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