Ultrastructure of convoluted proximal tubule of kidney mice before and after X-ray exposure

RESUMO

Ultrastructural initial changes study of convoluted proximal tubule after single dose of 154.8 mC/Kg (600R), X, ray whole body radiation was performed in 12C57BL mice. Twenty-four hours later, mitochondria evidenced proeminent changes such as cristolyses, dilatation and vacuolization. Within 72 hours, heterochromatin nuclei increased and vanished 144 hours after X-ray exposure. Such findings suggest that recovery probably happened because convoluted proximal tubules take place, regeneration occurs in aslow rate