Rabies virus in McCoy cell line. Part I - cytophatic effect and replication
Rev. Inst. Adolfo Lutz
;
52(1/2): 9-16, 1992. ilus, tab
Article
in English
| LILACS, SES-SP
| ID: lil-128445
ABSTRACT
The cytopathic effect caused by rabies virus is not easy to detect, although the McCoy cell line showed high sensitivity to this virus. The titre increased at each new passage and the ERA strain reached titre higher than 10(8.0)LD50/0,03ml after eight successive passages only. The kinetics of infection showed that 48 hours after inoculation, the cell reaches the peak of infecton and the celular proteins synthesis is inhibited. The data are reproducible suggesting that this cell line could be used for diagnostic purposes and for virus mass production
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Index:
LILACS (Americas)
Main subject:
Rabies virus
/
Cell Line
/
Cytopathogenic Effect, Viral
Language:
English
Journal:
Rev. Inst. Adolfo Lutz
Year:
1992
Type:
Article
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