Poliposis nasal: estudios fisiopatogénicos de diagnóstico y tratamiento / Nasal polyps: physiopathology study of diagnostic and treatment

ABSTRACT

Material and methods 20 patients with nasal polyps were successively studied. Personal and familiar history of atopy, evolution time, previous surgery, asthmatic crises, medication received, total IgE general and local eosiniphylia skin tests with inhalers, challenge tests with AAS and metacholine test were studied. Surgery was perfomed, histopathologic studies (hematoxylin eosin) and immunoperoxidases for IgG, IgM, IgA, IgE on sections were done. After this early study, patients were divided into 3 groups: group I: patients without brochial hyperreactivity (HRB (-)) without sensitivity to AAS (AAS(-)); Group II: patients HRG (+) AAS (-); Group III: patients HRG(+) AAS(+). Those patients with previous rhinoscopy and with hyperreactivity to metacholine were examined monthly during one year: their symptoms and medication, 3 patients from group II and 3 from Group III were selected. Half of them were prescribed beclomethasone, and the other half, beclomethasone + dexamethasone dipropionate cream locally applied