Leucemia prolinfocítica, descripción de dos casos / Prolymphocytic leukemia, description of 2 cases
Rev. méd. Chile
;
122(9): 1052-5, sept. 1994. ilus
Article
in Spanish
| LILACS
| ID: lil-138050
ABSTRACT
We present the clinical and laboratory features of 2 patients with B prolymphocitic leukemia. Both are females of the fith and seventh decade of life. One had the classical clinical picture of massive splenomegaly and a high white cell count, with characteristic prolymphocytes and the other was asymptomatic, with a low white cell count. The cells were positive to B cell lineage reagents with strong surface immunoglobuline (Ig) and unreactive to T cell antibodies. Analysis of Ig genes at the DNA level demonstrated that both cases had heavy-chain gene rearrangements, confirming the B-cell origin. These are the first patients of prolymphocytic leukemia described in Chile
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Index:
LILACS (Americas)
Main subject:
Leukemia, Prolymphocytic
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
1994
Type:
Article
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