Characterisation of phosphoprotein complexes associated with rat thymocyte Thy-1
Braz. j. med. biol. res
;
27(2): 269-73, Feb. 1994. ilus
Article
in English
| LILACS
| ID: lil-140263
ABSTRACT
We have previously demonstrated the non-covalent association of the protein tyrosine kinases p56lck and p60fyn together with a number of substrates for phosphorylation with rat thymocyte Thy-1. Here we present evidence that one of these associated phosphoproteins, p85, is associated by disulphide bridging with another polypeptide, demonstrating that it is an integral membrane protein with an extracellular domain. We also show that phosphatidylinositol 3 kinase activity may be coprecipitated with Thy-1 in Brij 96 thymocyte lysates
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Index:
LILACS (Americas)
Main subject:
Phosphatidylinositols
/
Phosphoproteins
/
Protein-Tyrosine Kinases
/
Membrane Glycoproteins
/
Glycolipids
/
T-Lymphocytes
Type of study:
Risk factors
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1994
Type:
Article
/
Congress and conference
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