Blood glucose and insulin response to intravenous glucose by patients with chronic Chagas' disease and alcoholism
Braz. j. med. biol. res
;
26(11): 1187-90, Nov. 1993. tab
Article
in English
| LILACS
| ID: lil-148822
RESUMO
Blood glucose and insulin responses to intravenous glucose 500 mg/kg in a group of alcoholic chagasic patients (Group I, N = 15) were assessed and compared to those of a group of patients with Chagas' disease without alcoholism (Group II, N = 16), a group of alcoholics without Chagas' disease (Group III, N = 22), and a group of non-alcoholics without Chagas' disease (Group IV, N = 15). Determinations of serum glucose and insulin were done under fasting conditions, 5 and 10 min after the injection of 50 per cent glucose. There was no difference in mean serum glucose levels between groups. Mean serum insulin levels at times 5 and 10 min and for the total integrated response were lower (P < 0.05) in Groups I and II as compared to Group IV; at time 10 min the mean was lower (P < 0.05) in Group III as compared to Group IV. There was a nonsignificant trend for a lower insulinemic response in Group I as compared to Group II. These data suggest denervation of or injury to pancreatic B cell by Chagas' disease
Search on Google
Index:
LILACS (Americas)
Main subject:
Blood Glucose
/
Chagas Disease
/
Alcoholism
/
Glucose
/
Insulin
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1993
Type:
Article
/
Congress and conference
Similar
MEDLINE
...
LILACS
LIS