Características cromosómicas asociadas con leucemias y otras hematopatías en Costa Rica / Chromosomie characteristics associated with leukemias and other hemathopathologies in Costa Rica
Rev. biol. trop
;
41(3A): 385-92, dic. 1993. ilus
Article
in Spanish
| LILACS
| ID: lil-152506
RESUMO
Chromosome analyses were performed on bone marrow and peripheral blood leucocytes of 117 patients with acute and chronic leukemias and myelodysplastic, myeloproliferative and hypereosinophilic syndromes, diagnosed in a Costa Rican hospital from May 1990 to July 1992. Cytogenetic diagnosis was achieved in 69.5 per cent of the 131 samples, the karyotype was normal in half of them. The most common chromosomal defect was the Philadelphia translocation, found in 80.5 per cent of the patients with chronic myelocitic leukemia as referral diagnosis and in some other cases. Other primary and secondary chromosomal abnnormalities were less frequent. The karotype analysis proved useful in clinical evaluation and management.
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Index:
LILACS (Americas)
Main subject:
Leukemia
Type of study:
Risk factors
Limits:
Adolescent
/
Adult
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Infant, Newborn
Country/Region as subject:
Central America
/
Costa Rica
Language:
Spanish
Journal:
Rev. biol. trop
Journal subject:
Biology
/
Tropical Medicine
Year:
1993
Type:
Article
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