Antígeno pre S1 en diferentes formas de infección con el virus de la hepatitis B / Pre S1 antigen in different forms hepatitis B virus infection
Rev. méd. Chile
;
123(5): 567-70, mayo 1995. tab
Article
in Spanish
| LILACS
| ID: lil-152858
ABSTRACT
Pre S1 antigen was measured using an ELISA technique in patients with different forms of hepatitis B virus infection. It was detected in 10 of 19 patients with acute hepatitis B (53 percent), 12 of 15 chronic hepatitis B virus carriers (80 percent), 9 of 11 patients with chronic hepatitis b (82 percent) and 3 of 4 patients with hepatoma and positive markers of hepatitis B virus infection. Pre S1 remained positive beyond 150 days in two patients with acute hepatitis that evolved to chronicity. Among subjects with chronic hepatitis B that received interferon, pre S1 antigen negativized only in the patient that had a complete response. Pre S1 detection is an index of hepatitis B virus replication and its persistence determines chronicity. Its negativization after antiviral therapy should have a predictive value
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Index:
LILACS (Americas)
Main subject:
Virus Replication
/
Hepatitis B virus
/
Hepatitis B
/
Hepatitis B Antigens
/
Hepatitis, Chronic
Type of study:
Prognostic study
Limits:
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
1995
Type:
Article
/
Project document
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