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The diameter of water pores formed by colicin la in planar lipid bilayers
Braz. j. med. biol. res ; 28(6): 693-8, Jun. 1995. graf
Article in English | LILACS | ID: lil-154940
RESUMO
The effective size of colicin Ia channel was tested by a recently described method 9FEMS, Microbiology and Immunology (1992). 105 93-100) in which the nonelectrolyte molecules with different hydrodynamic diameters (0.52 to 5.0nm) were used as molecular tools. We have shown that despite low conductance (55-105 pS at 1.5 MKCl, pH 7.0) the ion channels formed by colicin Ia have a fairly large water pore diameter equal to 1.66-1 1.88nm. The results are discussed in terms of an energetic barrier for ions passing into the channel lumen
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Index: LILACS (Americas) Main subject: Colicins / Ion Channels / Lipid Bilayers Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 1995 Type: Article

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Index: LILACS (Americas) Main subject: Colicins / Ion Channels / Lipid Bilayers Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 1995 Type: Article