Functional alterations of the autonomic nervous system in Chagas' heart disease
São Paulo med. j
;
113(2): 772-84, Mar.-Apr. 1995. graf
Article
in English
| LILACS
| ID: lil-161550
RESUMO
Several independent pathological studies in experimental models and in human beings showed conspicuous autonomic denervation in Chagas' disease. In spite of the inherently complex structural organization of the autonomic nervous system, the parasympathetic and sympathetic divisions are involved, as shown by many functional studies. Hence, Chagas' disease represents a unique model of impairment of the autonomic control of the heart, in absence of the nonspecific effects of cardiac failure. An important limitation of the studies thus far carried out is the lack of a better knowledge of the molecular biology characteristics of different strains of T. cruzi. This could explain some geographical discrepancies found in the clinical behaviour of Chagas' disease, and contribute to a better understanding of its pathophysiology.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Autonomic Nervous System
/
Chagas Cardiomyopathy
Type of study:
Prognostic study
Limits:
Adult
/
Humans
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
1995
Type:
Article
Similar
MEDLINE
...
LILACS
LIS