A brain soluble fraction inhibits synaptosomal membrane but not astrocyte ATPase activity
Medicina (B.Aires)
; 55(5/1): 431-4, 1995. graf
Article
in En
| LILACS
| ID: lil-161619
Responsible library:
BR1.1
RESUMO
Since a brain soluble fraction (peak II) is known to be able to inhibit synaptosomal membrane Na+, K+-ATPase activity, here we attempted to compare its effect on cellular and subcellular brain components such as synaptosomal and astrocytic membranes, as well as mitochondrial preparations. Peak II highly inhibited total ATPase in synaptosomal membranes but failed to modify enzyme activity in astrocytic and mitochondrial preparations. Findings suggest cellular and subcellular specificity of peak II on brain ATPase activity.
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Index:
LILACS
Main subject:
Subcellular Fractions
/
Synaptosomes
/
In Vitro Techniques
/
Cerebral Cortex
/
Sodium-Potassium-Exchanging ATPase
Limits:
Animals
Language:
En
Journal:
Medicina (B.Aires)
Journal subject:
MEDICINA
Year:
1995
Type:
Article