Evaluation of HTLV-I/II infection in blood donors in Buenos Aires
Medicina (B.Aires)
;
55(4): 295-9, 1995.
Article
in English
| LILACS
| ID: lil-161629
RESUMEN
HTLV-I and HTLV-II are two related retroviruses that are transmitted by sexual contact, breast feeding, blood transfusion and needle sharing. In this study the prevalence of HTLV-I and HTLV-II was evaluated in voluntary blood donors as a measure of the infection in the general population. Samples were tested by a gelatine particle agglutination test and repeatedly reactive samples were confirmed by Western blot tests (WBT), enriched with recombinant rgp21, rgp46I y rgp46II proteins, which differentiates HTLV-I and HTLV-II antibodies. Of 19,426 samples, 40 were repeatedly reactive by particle agglutination (0.21 percent). When analyzed by WBT, 6 met the criteria for HTLV-I (0.036 percent), 2 for HTLV-II (0.01 percent) and 1 for HTLV-I/II, 13 samples were indeterminate and 18 were negative. The prevalence is low and comparable to that from non endemic countries. Screening for anti HTLV-I/II antibodies is necessary to prevent transmission through blood transfusions.
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Index:
LILACS (Americas)
Main subject:
HTLV-I Infections
/
HTLV-II Infections
Type of study:
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Argentina
Language:
English
Journal:
Medicina (B.Aires)
Journal subject:
Medicine
Year:
1995
Type:
Article
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